Urticaria

The habones more or less big, pale and flanked of a reddish halo, generally very pruriginosos, of brief evolution, relapsing sometimes and that they can be disseminated by the whole surface of the skin, conatituyen the type of dermatosis called urticaria, for your similarity with the eruption that take place to the contact with the deadnettles. Besides the roncha and the cigar, the urticaria bud can accompany of other alterations, such as vessel spasms or intestinal, fever, tachycardia, hypotension, algias articulares, nauseas, among other.

The appearance rhythm and disappearance is extremely variable, and you give it place to two very well-known classes of this illness: the acute urticaria, with intense buds of disappearance in some hours or in a few days; and the chronic urticaria, with ronchas daily and in general less persistent pruritosas.

Of the meticulous, and sometimes difficult studio, of the lawsuits that can explain the intimate mechanism of this afecciñon, you concludes that the skin, in this case, the same as what happen for the mucous respratorias, has acquired a shade of sensibility or of answer in front of agents or diverse factors. If you are it due to specific alérgenos, and they act as such, in the maypría of the cases, those of alimentary type, or to hormonal psychic stimuli, physiques or infectious, at the same time that medicamentosos, constitutes an etiologic facet that the physician's sagacity will attempt desbozar.

If we add the importance that you/they sometimes acquire the local infections of the organism, centered in the intestine, appendix, kidney or teeth, we understand how difficult it can be the exhaustive studio of this illness.

In the case of the giant urticaria, angioedema or angioedema, you are from a similar eruption to that of the described urticaria, but with areas bigger and much deeper edematosas that invade the subcutaneous structures, besides the dermis. However actual base doesn't exist to consider these two processes like essentially different entities, since the same factors alergénicos are not able to unchain them.

If you affect the face, the edema it can end up acquiring such a big size that you impede the opening of the lids, and you are particularly important, due to the graveness that you had, the larynx edema, for the asphyxia hazard that you involve if you are not on time and meetly; you explain to it that, sometimes, you have to appeal to the tracheotomy.

Allergy to the Medicines

In general terms, the answer of our organism to the entry of a chemical substance with therapeutical ends obeys a laws that are subject to the share farmacodinámica of the used medicine whose toxicity grade or harmfulness has been studied previously. But it is not room for doubt that, in a certain number of patients, this pharmacological share theoretically foregone it escapes from the orbit of the communio one and the individual responds from an accidental way to the oral or parenteral management of a medicine. Doing without more or less of theories ingenious and truthful, it is possible that the accidents caused by the medicines can be classified in the following way:
1-high grade of toxicity of the used medicine and whose symptoms show up in most of the cases.
2-certain patients, for different reasons and as soon as determined, but not related with the allergy, they don't tolerate, like it is current, the chemical substances. To procure a pharmacological desirable share, it becomes precise to be administered them to much pettier and more unusual dose. We speak then of intolerance.
3-in some occasions, the effects that are expected are absolutely cross to those that it was logical to wait. It is about a personal paradox and it is for example what happens, when when giving an antihistamínico that averagely produces drowsiness, the individual it responds with a nervous general excitabilidad, desorbitada and unforeseeable; we could speak then of idiosyncrasy, in the sense fully etymological of the word.
4-in other cases, the fellow can enter, immediately to the entry of the medicine, whichever it is the nature of this and the contact modality, a type of divorced reaction completely dela nature of the substance and of his share farmacodinámica. It connects it with what the physicians are accustomed to see when they speak of syndromes anafilácticos or allergic. The word allergy should be reserved for this reaction type that involves a sensitization; it doesn't import now, and here, if in the antecedents they are allergy traces or not, and if they believe to know or on the contrary to ignore, the mechanism humoral or cellular that has unchained it.
5-finally, it exists another group of patients that, in front of the entry of a chemical substance of the type medicine, they unchain shocks with circulatory immediate failure that you/they very possibly owe you to the release of a substance called histamine whose pharmacological affection is the responsible for the serious dysfunctions. The relationships that can exist among the lawsuit, the allergic etiology and the pathogenetic unchaining mechanism, the histamine, they cannot be described here.

Until another type of anomalous answers to the medicines, such as those that in fact show up when discontinuing them; still in case, until that moment, they were very supported; it constitutes it an answer rarity that, for the unusual thing, we only mention it.

The clinical boxs to that the allergy medicamentosa can give place are extremely varied, I eat for example: shock of the type anafiláctico that is the most serious in these accidents; syndrome similar to the illness of the serum; fever medicamentosa, possibly many times to the own antibiotics and whose appearance suspicion outlines the physician a therapeutical query quite difficult of resolving; alterations cellular hemáticas; asthmatic crisis, rinitis and allergic conjunctivitis; cutaneous manifestations, of the erythema type, urticaria, edema, eczema; and hepatic, renal and gastrointestinal alterations.